Piperacillin sodium

SKU: orb1309380

Description

Piperacillin sodium is a semisynthetic penicillin antibiotic that induces bacterial cell lysis by inactivating penicillin-binding proteins (PBPs), thereby inhibiting cell wall synthesis. It is widely used in research to study antibacterial mechanisms and efficacy in both in vitro susceptibility assays and in vivo infection models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 59703-84-3
• MW: 539.54
• Purity: 99.66% (May vary between batches)
• Formula: C₂₃H₂₆N₅NaO₇S
• SMILES: [Na+].CCN1CCN(C(=O)NC(C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)c2ccccc2)C(=O)C1=O
• Target: Antibacterial,Antibiotic
• Solubility: H2O:92 mg/mL (170.52 mM);Ethanol:93 mg/mL (172.37 mM);DMSO:93 mg/mL (172.37 mM)

Bioactivity

• In Vivo:
  Piperacillin exhibits in vitro antibacterial activity against Gram-positive/Gram-negative and aerobic/anaerobic bacteria. It exerts its action by binding to penicillin-binding proteins, thereby inhibiting bacterial cell wall synthesis. Piperacillin is resistant to hydrolysis by various β-lactamases, including cephalosporinases, penicillinases, and broad-spectrum β-lactamases.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CL 227193, CL227193, CL-227193, Bacterial, Antibiotic, inhibit, Inhibitor, Sodium piperacillin, Piperacillin sodium, Piperacillin sodium salt, Piperacillin, β-Lactamase

Compound Identifiers

PubChem CID

23673309