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Pim-1/2 kinase inhibitor 2

SKU: orb2565470

Description

Pim-1/2 kinase inhibitor 2 is a competitive dual kinase inhibitor with IC50 values of 1.31 µM (PIM-1) and 0.67 µM (PIM-2). It demonstrates potent in vitro anticancer activity against several human cancer cell lines, including leukemia and solid tumors, while exhibiting low cytotoxicity toward normal Wi-38 fibroblasts.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2918764-16-4
MW458.9
FormulaC25H19ClN4O3
SMILESC(#N)C1=C(C=2C(=NC3=C(C2)C=C(Cl)C=C3)N4CCOCC4)C=C(NC1=O)C5=CC(O)=CC=C5
TargetPim

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information