PIASx (C) Antibody, Rabbit Polyclonal

SKU: orb66725

Description

Rabbit polyclonal to PIASx.PIASx is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator oftranscription)] family of transcriptional modulators. PIASx functions as an E3 small ubiquitin-likemodifier (SUMO) ligase. It stabilizes the interaction between UBE2I and the substrate, and functionsas a SUMO-tethering factor. PIASx plays an important role in transcriptional regulation of numerouscellular pathways, including the STAT pathway and the p53 pathway.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-ternimal region of human PIASxa
• Molecular Weight: 68
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-PIASx antibody,anti-MGC102682 antibody,anti-MIZ1 antibody,anti-PIASX antibody,anti-PIAS2 antibody,anti-PIASXBETA antibody,anti-SIZ2 antibody,anti-ZMIZ4 antibody,anti-miz antibody

Western blot analysis of total cell extracts from human Jurkat with control siRNA(Lane1),human Jurkat with PIASx siRNA(Lane2),mouse testis(Lane3) and human Jurkat(Lane4) using PIASx antibody

Quick Database Links

UniProt

O75928