PI3 Kinase p110 gamma Antibody

• Catalog Number: orb1731521
• Category: Antibodies
• Description: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: IP, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human PI3K-gamma
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 126 kDa; Observed MW: 110 kDa
• Entrez: 5294
• UniProt ID: P48736
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K
• Note: For research use only
• Expiration Date: 12 months from date of receipt.