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Catalog Number | orb1733137 |
---|---|
Category | Antibodies |
Description | Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser310 of human Presenilin 1 |
Concentration | 1mg/ml |
Dilution range | WB: 1/500-1/1000 |
Conjugation | Unconjugated |
MW | Calculated MW: 53 kDa; Observed MW: 22 kDa |
Entrez | 5663 |
UniProt ID | P49768 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protei Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
WB | |
Human | |
Rabbit | |
Monoclonal | |
Unconjugated |
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