Phospho-p21 Cip1 (Thr145) Antibody Discontinued

SKU: orb106145

Description

Rabbit polyclonal to p21 Cip1 (Phospho-Thr145). This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution Range: WB:1:500-1:2000, IHC-P:1:50-1:200
• Reactivity: Human, Mouse, Rat

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti CAP20 antibody, anti CDK-interacting protein 1 antibody, anti CDKN1 antibody, anti CDKN1A antibody, anti CDN1A antibody, anti CIP1 antibody, anti Cyclin-dependent kinase inhibitor 1 antibody, anti MDA-6 antibody, anti MDA6 antibody, anti Melanoma differentiation associated protein antibody, anti Melanoma differentiation antibody

Western blot analysis of EGF treated HeLa whole cell lysates using p21 Cip1 -Phospho-Thr145- antibody

Lehmann, Kuno et al. Liver failure after extended hepatectomy in mice is mediated by a p21-dependent barrier to liver regeneration Gastroenterology, 143, 1609-1619.e4 (2012)

PubMed: 22960658