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Catalog Number | orb1304927 |
---|---|
Category | Small Molecules |
Description | Phillyrin |
Purity | 98.76% |
MW | 534.55 |
Biological Activity | Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activation. Phillyrin(Forsythin) may be a new preventive agent of acute lung injury in the clinical setting, it potentially contributes to the suppression of the activation of MAPK and NF-κB pathways, it also has protective effects on H2O2-induced oxidative stress and apoptosis in PC12 cells. |
CAS Number | [487-41-2] |
Formula | C27H34O11 |
SMILES | COc1ccc(cc1OC)[C@@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC |
Storage | -20°C |
Note | For research use only |