Phenylbutazone

SKU: orb1224913

Description

Phenylbutazone(Butazolidin, Butatron) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis. Its use is limited by such severe side effects as suppression of white blood cell production and aplastic anemia. (In Vitro):Phenylbutazone has low inhibition of COX-1 and COX-2.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 50-33-9
• MW: 308.38
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₀N₂O₂
• SMILES: CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
• Target: COX
• Solubility: Ethanol: 62 mg/mL (201.05 mM); DMSO: 62 mg/mL (201.05 mM)

Bioactivity

• In Vitro:
  Phenylbutazone has low inhibition of COX-1 and COX-2.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Phenylbutazone | Fenilbutazona | Diphenylbutazone | Butapyrazole | Phenylbutazonum

Quick Database Links

Gene Symbol

COX