Phenylbutazone

SKU: orb1308640

Description

Phenylbutazone is a butyl-diphenyl-pyrazolidinedione compound with analgesic, antipyretic, and anti-inflammatory properties. It has been utilized in research models of rheumatoid arthritis, ankylosing spondylitis, and reactive arthritis, serving as a reference agent in both in vitro cyclooxygenase inhibition studies and in vivo inflammatory studies.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 50-33-9
• MW: 308.37
• Purity: 99.70% (May vary between batches)
• Formula: C₁₉H₂₀N₂O₂
• SMILES: CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
• Target: COX
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.49 mM);DMSO:55 mg/mL (178.36 mM);Ethanol:58 mg/mL (188.09 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ankylosing, Butazolidine, COX, Cyclooxygenase, MBNL1, Inhibitor, hepatotoxin, NSAID, inhibit, spondylitis, synthase, prostaglandin, PHS, Phenylbutazone

Compound Identifiers

PubChem CID

4781