Phenazopyridine hydrochloride

SKU: orb1308769

Description

Phenazopyridine hydrochloride (Pyridium) is an oral urinary analgesic with known side effects including nausea, methemoglobinemia, hemolytic anemia, and hepatorenal toxicity. It is also classified as a reasonably anticipated human carcinogen. This compound is used in research models investigating drug-induced toxicities and chemical carcinogenesis.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 136-40-3
• MW: 249.7
• Purity: 99.83% (May vary between batches)
• Formula: C₁₁H₁₂ClN₅
• SMILES: Cl.Nc1ccc(\N=N\c2ccccc2)c(N)n1
• Target: TRP/TRPV Channel,Sodium Channel
• Solubility: DMSO:10 mg/mL (40.05 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vivo:
  Phenazopyridine enhances cell viability, strengthens neuronal cell differentiation, synchronizes the state of cell differentiation, and reduces the number of non-neuronal and undifferentiated cells.
• In Vitro:
  Phenazopyridine directly inhibits the mechanical sensitivity of Aδ-fibers in the bladders of normal rats.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Pyridium, Phenazopyridine, Phenazopyridine Hydrochloride, Phenazopyridine HCl, Phenazopyridine hydrochloride, Sodium Channel, SodiumChannel, Urodine, Inhibitor, inhibit

Compound Identifiers

PubChem CID

8691