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PFI-4

SKU: orb1306909

Description

PFI-4

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number900305-37-5
MW380.44
Purity≥95%
FormulaC21H24N4O3
SMILESCOc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCCC1
TargetEpigenetic Reader Domain
SolubilityDMSO:14 mg/mL (36.8 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.63 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:5 mg/mL (13.14 mM)

Bioactivity

Target IC50
BRPF1:80 nM|BRPF3:>1 μM|BRPF2:7.9 μM
In Vitro
PFI-4 is cell permeable, and acts by displacin the BRPF1 bromodomain from Histone H3.3.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

BRPF3, BRPF2, BRPF1, bone loss, inhibit, osteoclasts, osteolytic malignant bone lesions, Inhibitor, Epigenetic Reader Domain, EpigeneticReaderDomain, PFI 4, PFI4, PFI-4

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    C21H24N4O3

    5 mg, 25 mg, 50 mg, 100 mg, 10 mg, 1 g, 500 mg, 200 mg
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Key Properties

No computed properties available.

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Protocol Information

PFI-4 (orb1306909)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 110.00
25 mg
$ 170.00
50 mg
$ 240.00
100 mg
$ 370.00
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