Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

PF-06928215

SKU: orb1218324

Description

PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).

Images & Validation

Key Properties

CAS Number2378173-15-8
MW380.4
Purity>98% (HPLC)
FormulaC20H20N4O4
SMILESOC1=CC(C2=CC=CC=C2)=NC3=C(C(N[C@H]4CCCC[C@H]4C(O)=O)=O)C=NN13
TargetcGAS
SolubilityDMSO:33.33 mg/mL (87.62 mM; Need ultrasonic)

Bioactivity

In Vitro
PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • PF-06928215 [orb1309258]

    98.95% (May vary between batches)

    2378173-15-8

    380.4

    C20H20N4O4

    5 mg, 10 mg, 25 mg, 100 mg, 1 ml x 10 mM (in DMSO), 50 mg, 1 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

200 mg
500 mg
5 mg
$ 310.00
10 mg
$ 440.00
25 mg
$ 830.00
50 mg
$ 1,190.00
100 mg
$ 1,670.00