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PF 03716556

SKU: orb1705324

Description

PF-03716556 (PF-3716556) is a potent and selective potassium-competitive acid blocker (P-CAB) used in research for gastroesophageal reflux disease (GERD). It serves as a key pharmacological tool for investigating gastric acid suppression in both in vitro assays and in vivo disease models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number928774-43-0
MW394.47
Purity99.95% (May vary between batches)
FormulaC22H26N4O3
SMILESCN(CCO)C(=O)c1cc(N[C@@H]2CCOc3cccc(C)c23)c2nc(C)cn2c1
TargetATPase,Proton pump
SolubilityDMSO:39.5 mg/mL (100.13 mM)

Bioactivity

Target IC50
H+, K+-ATPase:6.5(pIC50)
In Vivo
PF 03716556 is highly selective for H+ (pIC50=6.026),K+-ATPase (pIC50=7.095).
In Vitro
PF 03716556 is highly selective for H+ (pIC50=6.026),K+-ATPase (pIC50=7.095).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

H+/K+-ATPase, PF3716556, PF-3716556, PF 03716556, PF 3716556, PF-03716556, PF03716556

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 130.00
25 mg
$ 220.00
50 mg
$ 380.00
100 mg
$ 580.00
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