Petosemtamab Antibody

• Catalog Number: orb1980554
• Category: Antibodies
• Description: Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab can be used in the study of solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC).
• Target: Petosemtamab
• Clonality: Monoclonal
• Conjugation: Unconjugated
• Concentration: 6.98 mg/mL
• Purity: > 95%
• MW: 145.97 kDa
• CAS Number: 2213450-26-9
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only