Pergolide mesylate

SKU: orb1306044

Description

Pergolide mesylate is a long-acting dopamine D1/D2 receptor agonist historically used in Parkinson's disease and hyperprolactinemia research. Its investigation in both in vivo and in vitro models has been important for studying dopaminergic pathways, though clinical use was limited due to associated cardiac valvulopathy risks.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 66104-23-2
• MW: 410.59
• Purity: 99.70%
• Formula: C₂₀H₃₀N₂O₃S₂
• SMILES: CS(O)(=O)=O.CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13
• Target: 5-HT Receptor,Dopamine Receptor,Adrenergic Receptor
• Solubility: DMSO:55 mg/mL (133.95 mM);H2O:40 mg/mL (97.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.87 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

D2-receptor, D1-receptors, DopamineReceptor, Dopamine Receptor, Dopamine, 5-HT receptor, Adrenergic receptor, Adrenergic Receptor, AdrenergicReceptor, 5HT Receptor, 5HTReceptor, ergoline, MDA, hyperprolactinaemia, LY 127809, LY127809, LY-127809, Parkinson's, Pergolide methanesulfonate, Pergolide, Pergolide mesylate salt

Compound Identifiers

PubChem CID

47812