PDCD1 Antibody / PD-1 / PD1

• Catalog Number: orb1716185
• Category: Antibodies
• Description: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: PDCD1/7125
• Tested applications: ELISA, IHC-P
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: A portion of amino acids 1-200 from the human protein was used as the immunogen for the recombinant PDCD1 antibody.
• Dilution range: ELISA: for coating, order antibody without BSA,Immunohistochemistry (FFPE): 1-2ug/ml
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This recombinant PDCD1 antibody is available for research use only.
• UniProt ID: Q15116
• Storage: Aliquot the recombinant PDCD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Application notes: Optimal dilution of the recombinant PDCD1 antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.