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PD 117519

SKU: orb1299756

Description

PD 117519

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number96392-15-3
MW383.4
Purity99.98% (May vary between batches)
FormulaC19H21N5O4
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3Cc4ccccc4C3)ncnc12
TargetAdenosine Receptor
SolubilityDMSO:100 mg/mL (260.82 mM)

Bioactivity

In Vivo
PD 117519 selectively binds to adenosine A2 receptors (IC50 = 30 μM) over A1 receptors (IC50 = 810 μM) in rat brain membranes. PD 117519 increases heart rate and decreases systolic blood pressure in normotensive dogs when administered at doses of 2 or 10 mg/kg.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PD 117519, PD117519, PD-117519, inhibit, Inhibitor, A2, AdenosineReceptor, Adenosine Receptor, CI947, CI-947, CI 947, P1 receptor

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    C19H21N5O4

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 130.00
25 mg
$ 190.00
50 mg
$ 320.00
100 mg
$ 440.00
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