PAX2 (C) Antibody, Rabbit Polyclonal

SKU: orb67122

Description

Rabbit polyclonal to PAX2.Paired box protein Pax-2 is a probable transcription factor that may have a role in kidney celldifferentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Itinteracts with ELGN3; the interaction targets PAX2 for destruction. Defects in PAX2 are the cause ofrenal-coloboma syndrome CS) and may be responsible for isolated renal hypoplasia.

Research Area

Developmental Biology, Epigenetics, Neuroscience

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:2000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of human PAX2
• Molecular Weight: 45
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-PAX2 antibody,anti-Paired box protein Pax2 antibody

Western blot analysis of total cell extracts from mouse brain using PAX2 antibody

Quick Database Links

UniProt

Q02962