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Patritumab Antibody

SKU: orb1980647

Description

Patritumab (U3-1287) is a human monoclonal antibody targeting HER3, which exerts antitumor effects by inhibiting the phosphorylation of HER3, EGFR, HER2, ERK, and AKT pathways. It has demonstrated the ability to induce apoptosis and suppress proliferation in non-small cell lung cancer models in both in vitro and in vivo studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetEGFR|||ERK|||Akt|||HER
Molecular Weight146.97 kDa
Purity98.2% (SEC-HPLC) (May vary between batches)
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration2.71 mg/mL
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

U3-1287, ERK, EGFR, HER, AMG-888, Akt

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information

Available Sizes

Select a size below

1 mg
$ 340.00
5 mg
$ 830.00
10 mg
$ 1,270.00
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days
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