PARP1 Antibody

• Catalog Number: orb1732690
• Category: Antibodies
• Description: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 5C2
• Tested applications: IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Mouse IgG1
• Immunogen: Synthetic Peptide of Cleaved PARP
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100
• Conjugation: Unconjugated
• MW: Calculated MW: 113 kDa; Observed MW: 116 kDa
• Entrez: 142
• UniProt ID: P09874
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1
• Note: For research use only
• Expiration Date: 12 months from date of receipt.