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PARP (M) Antibody, Rabbit Polyclonal

Catalog Number: orb66938

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$ 440.00
Catalog Numberorb66938
CategoryAntibodies
DescriptionRabbit polyclonal to PARP.Poly [ADP-ribose] polymerase 1 (PARP) is involved in the base excision repair (BER) pathway bycatalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatinarchitecture and in DNA metabolism. This modification follows DNA damages and appears as anobligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARPpositively regulates the transcription of MTUS1 and negatively regulates the transcription ofMTUS2/TIP150.
ClonalityPolyclonal
Species/HostRabbit
ConjugationUnconjugated
ReactivityHuman
Buffer/Preservatives0.01% NaN3
PurityAffinity purification
Immunogenmiddle region of human PARP
UniProt IDQ3U1F9
MW113
Tested applicationsWB
Dilution rangeWB:1:1000-1:5000
Storage-20°C
Alternative namesanti-PARP antibody,anti-ADPRT antibody,anti-PPOL a
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NoteFor research use only
PARP (M) Antibody, Rabbit Polyclonal

Western blot analysis of total cell extracts from human Jurkat using PARP antibody