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| Catalog Number | orb1951492 |
|---|---|
| Category | Antibodies |
| Description | Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress. |
| Clonality | Recombinant |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG |
| Conjugation | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human PARK7 |
| UniProt ID | Q99497 |
| Tested applications | FC, ICC, IHC, IP, WB |
| Dilution range | WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 FC 1:50 |
| Antibody Type | Recombinant Antibody |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | Protein DJ-1; SP22; Protein DJ-1; Oncogene DJ1; Pa Read more... |
| Note | For research use only |
![PARK7 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951492_1.png)
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
![PARK7 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951492_2.png)
Immunohistochemical analysis of paraffin-embedded human bladder cancer, using PARK7 Antibody.
![PARK7 Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951492_3.png)
Western blot analysis of PARK7 expression in HeLa cell lysate.
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