p38 MAPK Rabbit mAb [KD Validated] Antibody

SKU: orb1951819

Description

Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6.

Research Area

Signal Transduction

Images & Validation

• Tested Applications: ChIP, FC, ICC, IP, WB
• Dilution Range: WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:30 ChIP 1:50
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human p38 MAPK
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CRK1; CSAID binding protein; CSBP; CSBP1; CSBP2; Cytokine suppressive anti- inflammatory drug binding protein; EC 2.7.11.24; MAP kinase MXI2; MAP kinase p38; MAPK14;

Quick Database Links

UniProt

Q16539