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p38 MAPK Inhibitor

SKU: orb1694119

Description

This small molecule p38 MAPK inhibitor exhibits potent activity with an IC50 of 35 nM. It effectively suppresses oncogenic RAS-induced senescence, making it a valuable tool for studying cellular aging, stress signaling, and cancer biology in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number219138-24-6
MW365.79
Purity99.96% (May vary between batches)
FormulaC20H13ClFN3O
SMILESO=C1C(=C(NN1C2=CC=C(Cl)C=C2)C=3C=CN=CC3)C4=CC=C(F)C=C4
Targetp38 MAPK
SolubilityDMSO:10 mg/mL (27.34 mM);Ethanol:0.3 mg/mL (0.82 mM);DMF:5 mg/mL (13.67 mM);DMSO:PBS(pH7.2) (1:1):0.5 mg/mL (1.37 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.73 mM)

Bioactivity

Target IC50
p38:35 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

p38 MAPK Inhibitor, p-38 MAPK Inhibitor, p38 MAPK, p38MAPK

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

500 μg
$ 100.00
1 mg
$ 130.00
5 mg
$ 350.00
10 mg
$ 530.00
25 mg
$ 760.00
50 mg
$ 1,020.00
100 mg
$ 1,340.00
200 mg
$ 1,810.00
DispatchUsually dispatched within 5-10 working days
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