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P-gp inhibitor 20

SKU: orb3133523

Description

P-gp inhibitor 20 (Compound H27) is a P-glycoprotein (P-gp) inhibitor characterized by low cytotoxicity. It reverses multidrug resistance (MDR) in MCF-7/ADR cells by inhibiting the efflux function of P-gp in a dose-dependent manner without affecting P-gp expression, with an IC50 value of 46.6 nM. P-gp inhibitor 20 is suitable for cancer research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC30H28N4O3Se
TargetP-gp

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information