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Oxatomide

SKU: orb2901545

Description

Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number60607-34-3
MW426.55
Purity>98% (HPLC)
FormulaC27H30N4O
SMILESO=C1NC2=C(C=CC=C2)N1CCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
Target5-HT Receptor
SolubilityIn Vitro: DMSO : 250 mg/mL (586.10 mM; Ultrasonic )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Protocol Information

Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 120.00
10 mg
$ 190.00
25 mg
$ 350.00
50 mg
$ 550.00
100 mg
$ 830.00
500 mg
$ 1,700.00