Others Antibody

SKU: orb3169687

Description

Anti-Nogo Receptor/NgR Antibody is a humanized monoclonal antibody targeting Nogo Receptor 1 (NgR1/RTN4R). NgR1 is a common receptor for CNS myelin-derived inhibitory factors (e.g., Nogo-A, MAG, and OMgp), the activation of which induces growth cone collapse and inhibits axonal regeneration. By specifically binding to NgR1, this antibody blocks the interaction between inhibitory ligands and the receptor, thereby lifting the restriction on neuronal growth and promoting axonal regeneration, compensatory sprouting, and synaptic plasticity. It is a vital tool for researching neural repair in spinal cord injury, stroke, and multiple sclerosis.

Key Properties

• Antibody Type: Inhibitor Antibody
• Clonality: Monoclonal
• Target: Others
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others