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Osunprotafib

SKU: orb1688337
FeaturedFeatured Product

Description

Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable inhibitor of PTP1B and PTPN2 currently in clinical trials for the treatment of solid tumors. It modulates the tumor microenvironment by boosting natural killer cell and CD8 T cell activity, enhancing anti-tumor immunity through activation of JAK–STAT signaling, and mitigating T cell dysfunction.

Images & Validation

Key Properties

CAS Number2489404-97-7
MW385.45
Purity97.11%
FormulaC17H24FN3O4S
SMILESCC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1
TargetPhosphatase

Storage & Handling

StoragePowder: -20°C
DisclaimerFor research use only

Alternative Names

Osunprotafib, AC484, AC 484, ABBV-CLS-484

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  • ABBV-CLS-484 [orb1818874]

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    2489404-97-7

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Osunprotafib

Cas No. 2489404-97-7

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Osunprotafib (orb1688337)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

130 mg
360 mg
1 mg
$ 560.00
5 mg
$ 1,460.00
10 mg
$ 2,250.00
25 mg
$ 3,830.00
50 mg
$ 5,030.00