Omigapil

SKU: orb3174212

Description

Omigapil (CGP3466B free base) is an orally active inhibitor of GAPDH nitrosylation that can prevent tau acetylation, memory deficits, and motor dysfunction induced by Aβ1-42 in mice, highlighting its potential for Alzheimer's disease research. It is an effective inhibitor of apoptosis and is applicable in studies of congenital muscular dystrophy (CMD). Additionally, Omigapil serves as a click chemistry reagent due to its Alkyne group, which can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide-containing molecules.

Research Area

Cell Biology

Key Properties

• CAS Number: 181296-84-4
• MW: 275.35
• Formula: C₁₉H₁₇NO
• SMILES: C#CCN(C)CC1=CC=2C=CC=CC2OC=3C=CC=CC31
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis