OM99-2

SKU: orb1690621

Description

OM99-2 is a potent eight-residue peptidomimetic inhibitor of human brain memapsin 2 (BACE1), with a Ki of 9.58 nM. It serves as a key research tool for studying BACE1 function and Aβ production in Alzheimer's disease, applicable in both in vitro enzymatic assays and cellular models.

Research Area

Neuroscience

Key Properties

• Target: Beta-Secretase
• CAS Number: 314266-76-7
• MW: 893.005
• Formula: C₄₁H₆₄N₈O₁₄
• SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)C(C)C)[C@@H](O)C[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

445649