OM99-2 TFA

SKU: orb1984536

Description

OM99-2 TFA is a potent, eight-residue peptidomimetic inhibitor of human brain memapsin 2 (BACE1) with a Ki of 9.58 nM. It serves as a key research tool for studying BACE1 function and inhibitor design in Alzheimer's disease, with applications in both in vitro enzymatic assays and cellular models.

Research Area

Immunology & Inflammation, Neuroscience

Key Properties

• Target: Beta-Secretase
• CAS Number: 2504147-81-1
• MW: 1007.028
• Formula: C₄₃H₆₅F₃N₈O₁₆
• SMILES: OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)C(C)C)[C@@H](O)C[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171360574