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Odanacatib

SKU: orb1224504

Description

A potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 0.2 nM; displays >300-fold selectivity over cathepsin B, L, S, F, and V; demonstrates the potentiation for the treatment of osteoporosis and other skeletal disorders associated with excessive bone remodeling.Osteoporosis Phase 3 Clinical.

Images & Validation

Key Properties

CAS Number603139-19-1
MW525.5588
Purity>98% (HPLC)
FormulaC25H27F4N3O3S
SMILESCC(C)(F)C[C@H](N[C@@H](C1=CC=C(C2=CC=C(S(=O)(C)=O)C=C2)C=C1)C(F)(F)F)C(NC3(C#N)CC3)=O
TargetCathepsin
SolubilityDMSO: ≥25 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MK-0822 | MK 0822 | MK0822

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Odanacatib (orb1224504)

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Available Sizes

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200 mg
500 mg
2 mg
$ 120.00
5 mg
$ 180.00
10 mg
$ 280.00
25 mg
$ 460.00
50 mg
$ 680.00
100 mg
$ 990.00