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Obtusin

SKU: orb1297262

Description

Obtusin

Research Area

Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number70588-05-5
MW344.32
Purity99.27% (May vary between batches)
FormulaC18H16O7
SMILESCOc1cc2C(=O)c3cc(C)c(O)c(OC)c3C(=O)c2c(O)c1OC
TargetMonoamine Oxidase,MAO
SolubilityDMSO:3.49 mg/mL (10.14 mM)

Bioactivity

Target IC50
MAO-A (human):11.12 μM
In Vitro
Nine anthraquinones, aurantio-Obtusin (1), chryso-Obtusin (2), Obtusin (3), chryso-Obtusin-2-O-beta-D-glucoside (4), physcion (5), emodin (6), chrysophanol (7), obtusifolin (8), and obtusifolin-2-O-beta-D-glucoside (9), isolated from an EtOAc-soluble extract of the seeds of Cassia tora, were subjected to in vitro bioassays to evaluate their inhibitory activity against advanced glycation end products (AGEs) formation and rat lens aldose reductase (RLAR).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anxiety, competitive, depression, hMAO-A, MAO, Inhibitor, human, inhibit, monoamine, Monoamine Oxidase, MonoamineOxidase, neurodegenerative, Obtusin, oxidase-A

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 80.00
50 ml x 5 mM (in DMSO)
$ 130.00
5 mg
$ 140.00
10 mg
$ 190.00