NVP-TAE 684

SKU: orb1305894

Description

NVP-TAE 684

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 761439-42-3
• MW: 614.2
• Purity: 99.91%
• Formula: C₃₀H₄₀ClN₇O₃S
• SMILES: N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(NC3=C(OC)C=C(C=C3)N4CCC(CC4)N5CCN(C)CC5)=NC=C2Cl
• Target: ALK,Apoptosis
• Solubility: DMSO:7.27 mg/mL (11.84 mM)

Bioactivity

• Target IC50:
  ALK:3 nM
• Cell Research:
  Cells are seeded in 384-well plates (2. × 04 cells per well) and incubated with serial dilutions of TAE684 or DMSO for 2–3 days. Luciferase expression is used as a measure of cell proliferation/survival and is evaluated wit the Bright-Glo Luciferase Assay System. IC50 Values are generated by using XLFit software.(Only for Reference)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

CD246, Cluster of differentiation 246, ALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, Anaplastic lymphoma kinase (ALK), Apoptosis, inhibit, NVP TAE 684, NVPTAE 684, NVP-TAE 684, NVP-TAE684, NVP-TAE-684, Inhibitor, TAE 684, TAE684, TAE-684

Compound Identifiers

PubChem CID

16038120