Rabies virus Nucleoprotein Mouse Monoclonal Antibody (MALS verified)

SKU: orb2986964

Description

The rabies virus nucleoprotein (N) is a highly conserved structural protein essential for viral replication. It tightly encapsulates the viral RNA genome, forming ribonucleoprotein complexes (RNPs) that protect the RNA and serve as templates for transcription/replication. The N protein of the CVS-11 strain (a challenge virus standard) is a major antigen that induces robust T-cell immunity and neutralizing antibodies. Anti-N antibodies are valuable tools for diagnosing rabies infection, studying viral morphogenesis, and developing vaccines or therapeutics due to N's high immunogenicity and cross-reactivity across lyssaviruses. Their specificity enables detection of viral RNPs in infected tissues.

Research Area

Infectious Disease & Virology; Immunology & Inflammation

Images & Validation

• Reactivity: Mouse

Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: Mouse IgG1 | Mouse Kappa
• Clone No.: 7B7
• Target: Nucleoprotein
• Source/Expression System: HEK293
• Purity: 0.95
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Nucleoprotein