NRIP1 (N) Antibody, Rabbit Polyclonal

SKU: orb67285

Description

Rabbit polyclonal to NRIP1.Nuclear receptor-interacting protein 1 (NRIP1) is also known as receptor-interacting protein 140IP140), which is a nuclear protein that specifically interacts with the hormone-dependent activationdomain AF2 of nuclear receptors. NRIP1 is a key regulator which modulates transcriptional activity ofa variety of transcription factors, including steroid receptors NR3C1, NR3C2 and ESR1. NRIP1 alsomodulates transcriptional repression by nuclear hormone receptors. NRIP1 has an important role inregulating lipid and glucose metabolism by regulating gene expression in metabolic tissues, includingheart, skeletal muscle and liver.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:2000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human NRIP1
• Molecular Weight: 127
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-NRIP1 antibody,anti-Nuclear receptorinteracting protein 1 antibody,anti-Nuclear factor RIP140 antibody,anti-Receptorinteracting protein 140 antibody

Western blot analysis of total cell extracts from human hela(Lane1) and mouse thymus(Lane2) using NRIP1 antibody

Quick Database Links

UniProt

P48552