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Nrf2-IN-4

SKU: orb3136303

Description

Nrf2-IN-4 is an Nrf2 inhibitor that induces ferroptosis by disrupting cellular iron homeostasis, promoting ferritin degradation, and ultimately triggering ferroptosis. It activates lysosomes through iron-dependent reactive oxygen species (ROS) production and lysosomal acidification. Nrf2-IN-4 demonstrates significant antitumor effects and is applicable in breast cancer research.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2417486-06-5
MW426.32
FormulaC20H13Cl2N5S
SMILESClC=1C=CC(=CC1Cl)C=2N=C(SC2)NN=C(C3=NC=CC=C3)C4=NC=CC=C4
TargetNrf2,Ferroptosis,ROS,ATG

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information