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Nrf2-IN-3

SKU: orb2900416

Description

Nrf2-IN-3 (Compound R16) is a Nrf2 inhibitor. Nrf2-IN-3 binds KEAP1 mutants (G333C mKEAP1) and repairs the disrupted KEAP1/NRF2 interactions. Nrf2-IN-3 sensitizes KEAP1-mutated cancer cells to Cisplatin (HY-17394) and Gefitinib (HY-50895) by repairing the mKEAP1/NRF2 complex.

Images & Validation

Key Properties

CAS Number6325-13-9
MW442.53
Purity>98% (HPLC)
FormulaC22H26N4O4S
SMILESO=C(NN=CC=1C=CC=CC1O)CCCSCCCC(=O)NN=CC=2C=CC=CC2O
TargetKeap1-Nrf2

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Available Sizes

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500 mg
2 mg
$ 220.00
5 mg
$ 320.00
10 mg
$ 500.00
25 mg
$ 940.00
50 mg
$ 1,480.00
100 mg
$ 2,350.00