Nrf2 degrader 1

• Catalog Number: orb2565648
• Category: Small Molecules
• Description: Nrf2 degrader 1 (compound 1), a PROTAC Nrf2 degrader, exhibits anticancer properties by inhibiting the growth of cancer cells. It demonstrates IC 50 values of 100 nM for A549 cells and 40 nM for LK-2 cells, indicating potent efficacy [1].
• CAS Number: 3025286-00-1
• Purity: 98.00%
• MW: 826.92
• SMILES: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOC4=CC(CC(NC5=NC(=C(C)S5)C=6C=C7C(=CC6)N(C(=O)C8=C(C)C=CC=C8)CC7)=O)=CC=C4
• Formula: C₄₅H₄₂N₆O₈S
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.