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NPB

SKU: orb1710789

Description

NPB (Alpha-NPB) is a potent small molecule inhibitor that blocks the phosphorylation of BAD at Ser99 with an IC50 of 0.41 µM. This compound is a valuable research tool for studying apoptosis regulation and BAD-related signaling pathways in both cellular and biochemical assays.

Research Area

Cell Biology, Neuroscience

Images & Validation

Key Properties

CAS Number2247491-97-8
MW524.48
Purity>99.99% (May vary between batches)
FormulaC29H31Cl2N3O2
SMILESOc1ccccc1C(N1CCN(CC1)c1cccc(Cl)c1Cl)c1cccc(c1)C(=O)NC1CCCC1
TargetOthers,Bcl-2 Family
SolubilityDMSO:45 mg/mL (85.8 mM)

Bioactivity

Target IC50
BAD Ser99:0.41 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Alpha-NPB, BAD, a-NPB, NPB, α-NPB

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 150.00
25 mg
$ 220.00
50 mg
$ 290.00
100 mg
$ 370.00
DispatchUsually dispatched within 5-10 working days
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