NPAS2 (M) Antibody, Rabbit Polyclonal

SKU: orb67299

Description

Rabbit polyclonal to NPAS2.Neuronal PAS domain-containing protein 2 (NPAS2) is a nuclear protein and a component of thecircadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2,CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. BMAL1-NPAS2 heterodimers activateE-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. Thistranscription is inhibited by a feedback loop mediated by PER, and also by CRY proteins.

Research Area

Cancer, DNA Damage, Epigenetics

Images & Validation

• Tested Applications: ChIP, WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: middle region of mouse NPAS2
• Molecular Weight: 91
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-NPAS2 antibody,anti-Neuronal PAS domaincontaining protein 2 antibody,anti-Neuronal PAS2 antibody

Western blot analysis of total cell extracts from human Hela using NPAS2 antibody

Quick Database Links

UniProt

P97460