Nourseothricin sulfate

SKU: orb1219760

Description

Nourseothricin sulfate is a broad-spectrum antibiotic,and inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi .Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions. Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin. There is a high degree of accumulation of Nourseothricin in renal cortical slices. In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation. Age dependent differences in Nourseothricin accumulation does not exist.

Key Properties

• CAS Number: 96736-11-7
• MW: 1359.47
• Purity: >98% (HPLC)
• Formula: C₅₀H₉₄N₂₀O₂₂S
• SMILES: O=S(=O)(O)O.NCCC[C@H](N)CC(=O)N[C@@H]3[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)O[C@H]3NC1=N[C@@H]2C(=O)NC[C@@H](O)[C@H]2N1.NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)N[C@@H]3[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)O[C@H]3NC=1N[C@@H]2[C@H](O)CNC(=O)[C@H]2N=1
• Target: Antibacterial
• Solubility: H2O:250 mg/mL (183.90 mM; Need ultrasonic)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Streptothricin sulfate

Quick Database Links

Gene Symbol

Antibacterial