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Notch inhibitor 1

SKU: orb1706903

Description

Notch inhibitor 1 is a potent small molecule targeting Notch signaling, with IC50 values of 7.8 nM and 8.5 nM for Notch 1 and Notch 3, respectively. It is widely applied in cancer research, utilized in both in vitro cellular assays and in vivo animal models to study tumor progression and therapeutic potential.

Research Area

Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1584647-27-7
MW574.49
FormulaC26H25F7N4O3
SMILESCc1cccc2c1NC(=O)[C@@H](NC(=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O)N=C2c1cccc(F)c1
TargetOthers,Gamma-secretase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information