(+)-Nortrachelogenin

SKU: orb1297081

Description

(+)-Nortrachelogenin is a bioactive lignan compound isolated from Wikstroemia indica. It has demonstrated antileukemic activity in research settings, showing potential for use in vitro studies investigating mechanisms of action against leukemia cell lines.

Research Area

Cell Biology, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 61521-74-2
• MW: 374.38
• Purity: 99.88%
• Formula: C₂₀H₂₂O₇
• SMILES: COc1cc(C[C@@H]2COC(=O)[C@@]2(O)Cc2ccc(O)c(OC)c2)ccc1O
• Target: Antifection,HIV Protease,PI3K,Apoptosis

Bioactivity

• In Vivo:
  (+)-Nortrachelogenin showed effects on the central nervous system producing depression in rabbits.
• In Vitro:
  (+)-Nortrachelogenin is moderately active against HIV-1 in vitro. (+)-Nortrachelogenin induces morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 microM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Phosphoinositide 3-kinase, Wikstromol, PI3K, Nortrachelogenin, inhibit, Inhibitor, HIV, HIV Protease, HIVProtease, Apoptosis, Antifection, (+)Nortrachelogenin, (+)-Nortrachelogenin, (+) Nortrachelogenin

Compound Identifiers

PubChem CID

479756