NOD1 antagonist-2

SKU: orb2945938

Description

NOD1antagonist-2 (compound 66) is a potent, selective, and orally bioavailable small molecule inhibitor of the NOD1 receptor, effective across human and murine systems. It suppresses NOD1-driven NF-κB and MAPK signaling pathways, making it a valuable tool for investigating NOD1's role in inflammation and immunity in both cellular and animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 3099180-63-6
• MW: 560.378
• Formula: C₂₁H₁₃Cl₂F₂N₃O₅S₂
• SMILES: CS(=O)(=O)C1=CC2=C(C=C1)N=C(N(C2=O)C3=CC(=C(C=C3)Cl)NS(=O)(=O)C4=C(C=CC=C4F)F)Cl
• Target: NOD-like Receptor (NLR)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676986