NOD1/2 antagonist-2

SKU: orb3174037

Description

NOD1/2 antagonist-2 (Compound 26BH) is a dual NOD1/NOD2 antagonist with IC50 values of 2.36 μM for NOD1 and 4.16 μM for NOD2. It inhibits the NF-κB and MAPK inflammatory signaling pathways, thereby enhancing the effect of Paclitaxel in inhibiting the growth of Lewis lung cancer.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2101736-25-6
• MW: 587.68
• Formula: C₃₂H₃₇N₅O₆
• SMILES: O=C1C=2C(=CC(NC(COCC3=CC=CC=C3)=O)=C(OC4=CC(N(C)C)=CC=C4)C2)NC(=O)[C@@H](CCC(NCCC)=O)N1
• Target: NOD-like Receptor (NLR)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NOD-like Receptor (NLR)