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NLRP3-IN-13

SKU: orb2900559

Description

NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1704638-35-6
MW365.41
Purity>98% (HPLC)
FormulaC19H15N3O3S
SMILESO=C1OC=2C=CC=CC2N1CC(=O)NCC3=CN=CC(=C3)C4=CSC=C4
TargetNOD
SolubilityIn Vitro: DMSO : 50 mg/mL (136.83 mM; Ultrasonic )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    99.16% (May vary between batches)

    1704638-35-6

    365.41

    C19H15N3O3S

    100 mg, 25 mg, 1 mg, 10 mg, 5 mg, 50 mg
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NLRP3-IN-13 (orb2900559)

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% DMSO +
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Available Sizes

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500 mg
2 mg
$ 130.00
5 mg
$ 180.00
10 mg
$ 260.00
25 mg
$ 540.00
50 mg
$ 800.00
100 mg
$ 1,220.00