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NLRP3-IN-13

SKU: orb1744493

Description

NLRP3-IN-13 is a selective small molecule inhibitor of the NLRP3 inflammasome, attenuating associated inflammatory responses. It is utilized in research on neuroinflammatory and neurodegenerative disorders, with studies demonstrating its activity in both cellular assays and animal models of disease.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number1704638-35-6
MW365.406
Purity99.16% (May vary between batches)
FormulaC19H15N3O3S
SMILESO=C(CN1C(=O)OC2=C1C=CC=C2)NCC1=CC(=CN=C1)C1=CSC=C1
TargetNOD-like Receptor (NLR),NOD
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.47 mM);DMSO:30 mg/mL (82.1 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NLRP3

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  • NLRP3-IN-13 [orb2900559]

    >98% (HPLC)

    1704638-35-6

    365.41

    C19H15N3O3S

    2 mg, 5 mg, 10 mg, 500 mg, 1 g, 100 mg, 25 mg, 50 mg
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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 100.00
5 mg
$ 170.00
10 mg
$ 240.00
25 mg
$ 500.00
50 mg
$ 730.00
100 mg
$ 1,130.00
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