NLRP3 agonist 1

SKU: orb1943097

Description

NLRP3 agonist 1 is a potent, orally bioavailable small molecule that directly activates the NLRP3 inflammasome, leading to Caspase-1-dependent cytokine maturation. It is a valuable research tool for studying inflammasome biology and inflammation-related diseases in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2454019-69-1
MW	280.33
Purity	99.01% (May vary between batches)
Formula	C₁₅H₁₆N₆
SMILES	N=1NC=CC1C=2C=CC3=C(N=C(N=C3NC4(C)CC4)N)C2
Target	Caspase,NOD,NOD-like Receptor (NLR)

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

154649381 ↗

Key Properties

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No computed properties available.

Protocol Information

Find More Protocols

CAS Number:	2143015-87-4
MW:	322.372
Formula:	C₁₇H₁₈N₆O

CAS Number:	5418-95-1
MW:	175.191
Formula:	C₈H₉N₅

Purity:	>98% (HPLC)
CAS Number:	987-65-5
MW:	551.14
Formula:	C₁₀H₁₄N₅O₁₃P₃·2Na

NLRP3 agonist 1

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

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