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NLRP3 agonist 1

NLRP3 agonist 1

Catalog Number: orb1943097

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Catalog Numberorb1943097
CategorySmall Molecules
DescriptionNLRP3 agonist 1 is an orally active and highly potent NLRP3 agonist that activates the enzyme Caspase-1, which may promote the maturation of pro-inflammatory cytokines.
Purity99.01%
MW280.33
Biological ActivityNLRP3 agonist 1 (compound 23) serves as a potent, orally active agent that activates Caspase-1 enzyme, leading to the cleavage of proinflammatory cytokines pro-IL-1β and pro-IL-18 into their active forms [1].
CAS Number2454019-69-1
FormulaC15H16N6
SMILESN=1NC=CC1C=2C=CC3=C(N=C(N=C3NC4(C)CC4)N)C2
Storage-20°C
NoteFor research use only
  • NLRP3 agonist 2 [orb1943098]

    98.00%

    50 mg, 5 mg
  • NPBA [orb2283547]

    98.00%

    524033-40-7

    353.3

    C16H14F3N3O3

    10 mg, 50 mg