Nicergoline

SKU: orb1309661

Description

Nicergoline is a semisynthetic ergot alkaloid derivative investigated for its potential in treating cognitive disorders of vascular origin, such as senile dementia. Research applications include in vitro studies on neuroprotection and in vivo models of cerebral ischemia and cognitive impairment.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 27848-84-6
• MW: 484.39
• Purity: 99.80%
• Formula: C₂₄H₂₆BrN₃O₃
• SMILES: O(C)[C@@]12C=3C=4C(C[C@]1(N(C)C[C@H](COC(=O)C=5C=C(Br)C=NC5)C2)[H])=CN(C)C4C=CC3
• Target: Adrenergic Receptor
• Solubility: DMSO:50 mg/mL (103.22 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.13 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

vasodilator, α1A, Inhibitor, inhibit, Nicergoline, Nicergolinum, Nimergoline, AdrenergicReceptor, adrenoceptor, Adrenergic Receptor, Alzheimer's, bromonicotinic, Beta Receptor, disease

Compound Identifiers

PubChem CID

34040